ACE-031 1mg Myostatin Inhibitor

ACE-031 is a recombinant fusion protein that functions as a myostatin inhibitor, designed to enhance muscle mass, strength, and recovery through the regulation of the myostatin (GDF-8) signaling pathway.

At West Lab Chemicals, we supply ACE-031 1mg (Research Grade) with ≥98% purity (HPLC & SDS-PAGE verified) for scientific, biochemical, and in vitro research.

This protein is commonly studied in the context of muscle wasting disorders, sarcopenia, and muscle regeneration therapies, providing an essential tool for muscle growth research and tissue regeneration studies.

What is ACE-031?

ACE-031 (Activin Receptor Type IIB-Fc) is a synthetic recombinant fusion protein composed of the extracellular domain of human ActRIIB linked to the Fc domain of human IgG1.

It functions as a myostatin pathway modulator — binding and neutralizing myostatin (GDF-8) and related ligands that limit muscle growth.
By inhibiting myostatin signaling, ACE-031 allows for increased muscle hypertrophy, enhanced repair, and improved metabolic activity in muscle tissues.

Originally developed for muscle wasting conditions, it is now a key focus in academic and pharmaceutical muscle regeneration research.

Key Features

✅ ≥98% purity (HPLC and SDS-PAGE verified)
✅ Recombinant fusion protein (ActRIIB-Fc)
✅ Potent myostatin and activin inhibitor
✅ Supports muscle growth, repair, and recovery studies
✅ Enhances protein synthesis and muscle hypertrophy
✅ Research-grade for laboratory use only
✅ Supplied with COA and purity validation data

Benefits (Research Context)

⚙️ Myostatin Inhibition: Blocks negative regulation of muscle growth via the GDF-8 pathway.
⚙️ Muscle Regeneration: Stimulates repair and recovery of damaged muscle fibers.
⚙️ Enhanced Muscle Mass: Promotes hypertrophy in in vitro and preclinical models.
⚙️ Anti-Catabolic Effects: Prevents muscle degradation in atrophy conditions.
⚙️ Synergistic Research: Complements peptides like Follistatin, BPC-157, and PEG-MGF.

Applications / Uses (Research Only)

🔹 Myostatin inhibition and signaling studies
🔹 Muscle hypertrophy and regeneration research
🔹 Sarcopenia and cachexia model experiments
🔹 Protein synthesis and muscle metabolism research
🔹 Preclinical evaluation of anabolic signaling pathways

Composition & Technical Data

Dosage & Usage (Research Context)

• Recommended concentration: As determined by individual research objectives

• Solvent: Reconstitute with sterile water for injection or PBS buffer

• Storage after reconstitution: Store aliquots at –20 °C

• Handling: Avoid repeated freeze–thaw cycles

• Note: For research use only; not for human or veterinary use, not for injection or consumption

Storage & Stability

• Store dry powder at –20 °C in a sealed vial.

• After reconstitution, aliquot and store at –80 °C for long-term use.

• Protect from repeated freeze–thaw cycles, heat, and moisture.

• Maintain aseptic conditions during reconstitution and handling.

Safety & Handling

• For laboratory and research use only.

• Not approved for human use, consumption, or therapeutic applications.

• Avoid direct contact with skin and mucous membranes.

• Handle using gloves, lab coat, and protective eyewear.

• Dispose of all waste material following institutional biosafety protocols.

Why Buy from West Lab Chemicals?

🌐 Verified Purity: ≥98% confirmed by HPLC & SDS-PAGE.
🧪 GMP-Grade Manufacturing: Consistent, sterile, and traceable production.
📄 Full Documentation: COA & MSDS supplied with every batch.
🚚 Global Shipping: Fast, temperature-controlled worldwide delivery.
💬 Technical Expertise: Expert support for reconstitution and lab handling.
💧 Trusted by Researchers: Premium-grade peptides and proteins for reliable lab performance.

Purity Guarantee

Each vial of ACE-031 (1mg) from West Lab Chemicals undergoes:

• ≥98% HPLC and SDS-PAGE purity confirmation

• Endotoxin and microbial testing

• COA batch traceability

• Sterile filtration and freeze-drying

• Verified protein integrity and folding