⚗️ AICAR 50mg | AMPK Activator | Metabolic & Endurance Research Peptide | West Lab Chemicals

Product Overview

AICAR (5-Aminoimidazole-4-carboxamide ribonucleotide) is a cell-permeable activator of AMPK (AMP-activated protein kinase) — an enzyme that plays a key role in cellular energy regulation, glucose metabolism, and endurance enhancement.

At West Lab Chemicals, we offer AICAR 50mg (Research Grade) with ≥99% purity (HPLC verified), specifically formulated for scientific, biochemical, and metabolic pathway research.

AICAR is used in laboratories to study energy metabolism, insulin sensitivity, and exercise-mimetic pathways that regulate fat oxidation and mitochondrial biogenesis.

What is AICAR?

AICAR, also known as Acadesine, is an AMP analog that enters cells and is converted into ZMP (AICA ribotide) — a compound that mimics AMP, thus activating AMPK, the body’s energy-sensing enzyme.

Through AMPK activation, AICAR triggers cellular pathways similar to those activated during aerobic exercise, making it a valuable tool for research in:

• Glucose uptake and insulin signaling

• Fat metabolism and mitochondrial activity

• Endurance enhancement studies

• Metabolic and cardiovascular disease models

Key Features

✅ ≥99% purity verified by HPLC
✅ Potent AMPK pathway activator
✅ Enhances glucose uptake and lipid oxidation
✅ Mimics metabolic effects of endurance exercise
✅ Improves mitochondrial efficiency in research models
✅ Ideal for metabolic, obesity, and exercise physiology research

Benefits (Research Context)

⚙️ Energy Regulation: Activates AMPK to improve cellular energy balance.
⚙️ Glucose Control: Enhances glucose transport independent of insulin.
⚙️ Lipid Metabolism: Promotes fat oxidation and inhibits lipid synthesis.
⚙️ Endurance Mimetic: Induces exercise-like metabolic responses in muscle tissue.
⚙️ Mitochondrial Function: Stimulates biogenesis and oxidative metabolism.

Applications / Uses (Research Only)

🔹 Metabolic and mitochondrial research
🔹 AMPK signaling and activation studies
🔹 Diabetes and insulin sensitivity models
🔹 Exercise physiology and endurance research
🔹 Energy regulation and cell metabolism experiments

Composition & Technical Data

Dosage & Usage (Research Context)

• Recommended concentration: As determined by specific research protocol

• Solvent: Reconstitute in sterile water or phosphate-buffered saline (PBS)

• Storage after reconstitution: Store aliquots at –20 °C

• Handling: Avoid repeated freeze–thaw cycles

• Note: For in vitro and laboratory research use only; not for injection or ingestion

Storage & Stability

• Store dry powder at –20 °C in a sealed vial.

• Protect from heat, light, and humidity.

• After reconstitution, aliquot immediately and freeze for long-term storage.

• Maintain aseptic technique during preparation.

Safety & Handling

• For research use only — not for human or veterinary use.

• Avoid direct contact with skin, eyes, and mucous membranes.

• Use gloves and appropriate lab PPE during handling.

• Dispose of waste according to institutional biosafety protocols.

Why Buy from West Lab Chemicals?

🌐 Verified Purity: ≥99% confirmed via HPLC & MS analysis.
🧪 GMP-Compliant Manufacturing: Reliable and reproducible research-grade quality.
📄 Documentation Included: COA and MSDS supplied with each batch.
🚚 Global Shipping: Fast, temperature-controlled worldwide delivery.
💬 Technical Expertise: Research support for solubility, reconstitution, and usage.
💧 Trusted Worldwide: Leading supplier for peptides, amino analogs, and metabolic research compounds.

Purity Guarantee

Each batch of AICAR 50mg from West Lab Chemicals undergoes:

• HPLC purity testing (≥99%)

• Mass Spectrometry verification

• Microbial and endotoxin screening

• COA batch traceability

• Research-grade certification