FOX04-DRI 10mg | Senolytic Peptide | Cellular Senescence & Longevity Research | West Lab Chemicals

Product Overview

FOX04-DRI (D-Retro-Inverso FOXO4 peptide) is a synthetic research peptide designed to selectively target senescent cells and promote apoptosis (programmed cell death) in dysfunctional, aging cells.

At West Lab Chemicals, we supply FOX04-DRI 10mg (Research Grade) with ≥99% purity (HPLC & MS verified), manufactured in GMP-certified facilities to ensure maximum stability, potency, and purity.

This peptide is widely used in senescence, longevity, and cellular repair research, exploring the mechanisms behind aging reversal, cellular rejuvenation, and tissue regeneration.

What is FOX04-DRI?

FOX04-DRI (D-Retro-Inverso FOXO4 Peptide) is a synthetic analog of a natural sequence within the FOXO4 protein — a transcription factor that interacts with p53, a major regulator of cell cycle and apoptosis.

In senescent (aging) cells, the FOXO4–p53 interaction prevents apoptosis, allowing dysfunctional cells to persist. FOX04-DRI disrupts this binding, selectively triggering apoptosis in senescent cells while sparing healthy ones.

This unique mechanism has positioned FOX04-DRI as a key research tool in anti-aging, regenerative, and cancer biology studies.

Key Features

✅ ≥99% purity verified by HPLC & Mass Spectrometry
✅ Selectively targets senescent (aging) cells in research
✅ Disrupts FOXO4–p53 protein binding
✅ Induces apoptosis in damaged cells (research context)
✅ Supports tissue rejuvenation and cellular regeneration studies
✅ Non-hormonal, peptide-based mechanism
✅ GMP-certified production and full COA provided

Benefits (Research Context)

⚙️ Senescent Cell Removal: Promotes apoptosis in aged or damaged cells.
⚙️ Cellular Rejuvenation: Supports studies on tissue regeneration and longevity.
⚙️ DNA Repair Research: Explores pathways of genomic stability and repair.
⚙️ Anti-Aging Mechanisms: Studies in reversal of cellular senescence.
⚙️ Neuroprotective Potential: Early-stage research into brain aging and neurodegeneration.

Applications / Uses (Research Only)

🔹 Cellular senescence and longevity studies
🔹 Regenerative medicine and anti-aging research
🔹 Cancer biology and apoptosis signaling models
🔹 p53–FOXO4 protein interaction pathway studies
🔹 Genomic stability and oxidative stress experiments

Composition & Technical Data

Dosage & Usage (Research Context)

• Reconstitution: Dissolve in sterile water, PBS, or DMSO.

• Concentration: Determined by experimental protocol.

• Storage after reconstitution: Store aliquots at –20 °C.

• Handling: Avoid repeated freeze–thaw cycles.

• Note: For in vitro research use only — not for injection or ingestion.

Storage & Stability

• Store lyophilized FOX04-DRI at –20 °C for long-term preservation.

• After reconstitution, store at 2–8 °C and use within 30 days.

• Protect from light, moisture, and temperature fluctuations.

• Maintain aseptic handling to preserve purity.

Safety & Handling

• For scientific and laboratory research use only.

• Not approved for human or veterinary use.

• Avoid contact with skin, eyes, and mucous membranes.

• Handle with gloves and laboratory PPE.

• Dispose of materials according to institutional biosafety regulations.

Why Buy from West Lab Chemicals?

🌐 Laboratory-Verified Purity: ≥99% confirmed via HPLC & MS.
🧪 GMP-Compliant Production: Ensures consistent peptide quality.
📄 COA & MSDS Included: Full documentation with every batch.
🚚 Global Shipping: Fast, temperature-controlled worldwide delivery.
💬 Technical Expertise: Assistance with peptide handling and reconstitution.
💧 Trusted Worldwide: Preferred by longevity, oncology, and cellular biology researchers.

Purity Guarantee

Each vial of FOX04-DRI 10mg from West Lab Chemicals undergoes:

• HPLC purity testing (≥99%)

• Mass spectrometry validation

• Microbial and endotoxin testing

• Batch-specific COA verification

• GMP & ISO 9001:2015 certified production