Fragment 176-191 5mg | Growth Hormone Fragment | Fat Metabolism & Lipolysis Research

Fragment 176-191 is a synthetic peptide fragment derived from the C-terminal region of the human Growth Hormone (hGH) molecule.
This 13-amino acid sequence (positions 176–191) is responsible for GH’s fat-metabolizing (lipolytic) properties but does not exhibit the proliferative or diabetogenic effects of full-length Growth Hormone.

At West Lab Chemicals, we supply Fragment 176-191 5mg (Research Grade) with ≥99% purity (HPLC verified), produced under GMP-certified conditions to ensure exceptional stability, purity, and reliability for metabolic and obesity research.

What is Fragment 176-191?

Growth Hormone Fragment 176-191 is a bioactive peptide segment of Human Growth Hormone (hGH) that specifically targets adipose tissue metabolism.
It mimics the fat-reducing (lipolytic) effects of GH without affecting blood glucose levels or growth factors.

Mechanism of Action

Fragment 176-191 acts by:

• Enhancing lipolysis (fat breakdown)

• Inhibiting lipogenesis (fat formation)

• Stimulating beta-adrenergic receptor pathways

• Increasing energy expenditure and fat oxidation

This makes it a valuable research compound for metabolic, obesity, and energy regulation studies.

Key Features

✅ ≥99% purity verified by HPLC & MS
✅ Mimics the lipolytic region of Human Growth Hormone
✅ Promotes fat metabolism and oxidation (research context)
✅ Non-hormonal, tissue-specific mechanism
✅ Stable lyophilized form for precision research
✅ Manufactured in GMP-certified laboratories

Benefits (Research Context)

⚙️ Fat Metabolism Studies: Promotes adipose tissue lipolysis in cell culture models.
⚙️ Metabolic Research: Helps explore pathways of fat oxidation and energy balance.
⚙️ Obesity Mechanism Studies: Demonstrates anti-lipogenic effects without GH side effects.
⚙️ Glucose Regulation: No significant impact on insulin sensitivity (research data).
⚙️ Safe Profile: Does not affect cell proliferation or glucose uptake mechanisms.

Applications / Uses (Research Only)

🔹 Lipolysis and adipose tissue research
🔹 Obesity and fat metabolism studies
🔹 Growth hormone pathway investigations
🔹 Energy regulation and mitochondrial activity experiments
🔹 Endocrine and metabolic modeling

Composition & Technical Data

Dosage & Usage (Research Context)

• Reconstitution: Dissolve in sterile or bacteriostatic water.

• Recommended concentration: As defined by study parameters.

• Storage after reconstitution: Store aliquots at –20 °C.

• Handling: Avoid repeated freeze–thaw cycles.

• Note: For in vitro research use only — not for injection or ingestion.

Storage & Stability

• Store lyophilized powder at –20 °C for up to 24 months.

• Once reconstituted, refrigerate (2–8 °C) and use within 30 days.

• Protect from light, moisture, and heat.

• Handle under sterile laboratory conditions.

Safety & Handling

• For scientific and laboratory research use only.

• Not for human or veterinary use.

• Avoid inhalation or direct skin contact.

• Use gloves, mask, and lab safety equipment.

• Dispose of according to institutional biosafety regulations.

Why Buy from West Lab Chemicals?

🌐 Verified Purity: ≥99% confirmed by HPLC & MS.
🧪 GMP-Compliant Manufacturing: Ensures consistency and sterility.
📄 COA & Documentation: Certificate of Analysis provided with each vial.
🚚 Worldwide Delivery: Temperature-controlled global shipping.
💬 Technical Support: Assistance for reconstitution and peptide handling.
💧 Trusted Source: Preferred by metabolic and endocrine research labs worldwide.

Purity Guarantee

Each batch of Fragment 176-191 5mg from West Lab Chemicals undergoes:

• ≥99% HPLC & MS purity testing

• Microbial and endotoxin screening

• COA batch validation

• GMP & ISO 9001:2015 certified manufacturing