GLP-2 “TZ” 50mg | Glucagon-Like Peptide-2 Analog | Intestinal Regeneration & Gut Barrier Research | West Lab Chemicals

Product Overview

GLP-2 “TZ” (Glucagon-Like Peptide-2 Analog) is a synthetic peptide analog of the natural hormone GLP-2, a critical regulator of intestinal growth, nutrient absorption, and mucosal repair.

At West Lab Chemicals, we offer GLP-2 “TZ” 50mg (Research Grade) with ≥99% purity (HPLC & MS verified), produced in GMP-certified peptide laboratories to ensure absolute purity, structural integrity, and biological consistency.

This long-acting analog is commonly used in gastrointestinal, metabolic, and mucosal biology research, where it facilitates studies related to intestinal epithelial regeneration, gut permeability, and enterocyte proliferation.

What is GLP-2 “TZ”?

GLP-2 “TZ” is a stabilized, synthetic form of Glucagon-Like Peptide-2 (GLP-2), a naturally secreted 33-amino acid hormone produced by intestinal L-cells in response to nutrient ingestion.

The “TZ” modification increases resistance to DPP-IV enzymatic degradation, extending its half-life and biological activity in research applications.

GLP-2 analogs like “TZ” are vital tools for exploring intestinal adaptation, tissue regeneration, and mucosal healing under controlled experimental conditions.

Mechanism of Action

• Binds to GLP-2 receptors (GLP-2R) in intestinal epithelial and submucosal tissues.

• Stimulates crypt cell proliferation and villus elongation.

• Reduces apoptosis and supports epithelial repair.

• Activates IGF-1 and PI3K/Akt pathways, enhancing tissue regeneration.

• Strengthens intestinal barrier function and nutrient uptake.

Key Features

✅ ≥99% purity confirmed by HPLC & Mass Spectrometry
✅ Long-acting GLP-2 analog with superior stability
✅ Promotes epithelial regeneration and mucosal protection
✅ DPP-IV–resistant for extended bioactivity
✅ GMP-certified production with full documentation
✅ Convenient 50mg vial ideal for ongoing gastrointestinal studies

Benefits (Research Context)

⚙️ Intestinal Regeneration: Stimulates cell proliferation and crypt-villus growth.
⚙️ Mucosal Barrier Repair: Supports epithelial restoration and wound closure.
⚙️ Nutrient Absorption: Enhances glucose, amino acid, and lipid transport in GI models.
⚙️ Anti-Inflammatory Response: Reduces cytokine-induced tissue damage.
⚙️ Barrier Integrity: Strengthens tight junctions and mucosal resilience in research assays.

Applications / Uses (Research Only)

🔹 Gastrointestinal mucosal healing and tissue repair studies
🔹 Intestinal barrier and permeability experiments
🔹 IBD, Crohn’s, and enteric inflammation models
🔹 Nutrient absorption and metabolic regulation research
🔹 Endocrine and enteric signaling pathway studies

Composition & Technical Data

Dosage & Usage (Research Context)

• Reconstitution: Dissolve in sterile or bacteriostatic water.

• Working concentration: Determined by specific research design.

• Storage after reconstitution: Keep at –20 °C and avoid repeated freeze–thaw cycles.

• Note: For in vitro and laboratory research only — not for injection or ingestion.

Storage & Stability

• Store lyophilized peptide at –20 °C for up to 24 months.

• Reconstituted peptide should be stored at 2–8 °C and used within 30 days.

• Protect from light, moisture, and heat.

• Always handle using aseptic laboratory techniques.

Safety & Handling

• Intended for scientific research use only.

• Not for human or veterinary administration.

• Avoid inhalation, ingestion, or direct contact with skin.

• Use gloves, safety goggles, and PPE when handling.

• Dispose of materials according to institutional biosafety standards.

Why Buy from West Lab Chemicals?

🌐 Unmatched Purity: ≥99% verified via HPLC and MS testing.
🧪 GMP Production: Ensures sterility, consistency, and repeatability.
📄 Full Documentation: COA & MSDS provided with each batch.
🚚 Global Distribution: Temperature-controlled shipping available worldwide.
💬 Technical Support: Expert guidance on solubility, formulation, and storage.
💧 Trusted Worldwide: Used by researchers in regenerative and gastrointestinal studies.

Purity Guarantee

Each vial of GLP-2 “TZ” 50mg from West Lab Chemicals undergoes:

• ≥99% purity verification by HPLC & MS

• Endotoxin and sterility testing

• COA batch traceability

• GMP & ISO 9001:2015 certified manufacturing standards