Humanin 10mg | Mitochondrial Peptide | Neuroprotective & Longevity Research | West Lab Chemicals

Product Overview

Humanin is a naturally occurring mitochondrial-derived peptide (MDP) consisting of 24 amino acids, renowned for its powerful cytoprotective, anti-apoptotic, and neuroprotective effects.

At West Lab Chemicals, we supply Humanin 10mg (Research Grade) with ≥99% purity (HPLC & MS verified), produced under GMP-certified laboratory conditions for guaranteed stability, purity, and bioactivity.

Humanin is a central peptide in aging, mitochondrial signaling, and cellular stress-response research, where it helps scientists investigate longevity mechanisms, neurodegenerative protection, and metabolic regulation.

What is Humanin?

Humanin is a mitochondrial peptide first discovered in the hypothalamus and later found to be encoded within the mitochondrial 16S rRNA gene.

It is part of a class of Mitochondrial-Derived Peptides (MDPs) that act as cellular defense molecules, protecting cells from oxidative damage, apoptosis, and mitochondrial dysfunction.

Research suggests Humanin plays a significant role in metabolic regulation, neuroprotection, and cellular longevity, making it a highly valuable tool for studying aging biology and age-related disease models.

Mechanism of Action

• Binds to Humanin receptors (FPRL1 and CNTFR/WSX-1/gp130 complex) on cell surfaces.

• Inhibits apoptotic pathways triggered by pro-apoptotic factors like Bax and IGFBP-3.

• Activates pro-survival pathways (STAT3, ERK1/2, and PI3K/Akt).

• Enhances mitochondrial function and energy production.

• Regulates oxidative stress and inflammatory signaling cascades.

Key Features

✅ ≥99% purity verified by HPLC & MS
✅ Synthetic Humanin peptide (identical to native mitochondrial form)
✅ Supports longevity, anti-apoptotic, and neuroprotective research
✅ GMP-certified peptide manufacturing
✅ 10mg vial — ideal for mid- to large-scale studies
✅ COA & MSDS documentation included

Benefits (Research Context)

⚙️ Neuroprotection: Prevents neuronal apoptosis in neurodegenerative models.
⚙️ Mitochondrial Support: Enhances energy metabolism and mitochondrial efficiency.
⚙️ Longevity Studies: Extends cellular survival and resilience to oxidative stress.
⚙️ Cardiovascular Protection: Demonstrates cytoprotective and anti-inflammatory effects in vascular tissues.
⚙️ Metabolic Regulation: Modulates insulin sensitivity and glucose homeostasis in research models.

Applications / Uses (Research Only)

🔹 Mitochondrial and longevity peptide research
🔹 Neurodegenerative and Alzheimer’s disease models
🔹 Metabolic and insulin sensitivity studies
🔹 Oxidative stress and cell protection assays
🔹 Aging and regenerative biology experiments

Composition & Technical Data

Dosage & Usage (Research Context)

• Reconstitution: Dissolve in sterile or bacteriostatic water before use.

• Concentration: Adjust based on experimental design.

• Storage after reconstitution: Store aliquots at –20 °C.

• Handling: Avoid multiple freeze–thaw cycles.

• Note: For in vitro and laboratory research only — not for human or veterinary use.

Storage & Stability

• Stable for 24 months at –20 °C (lyophilized).

• Once reconstituted, store at 2–8 °C for up to 30 days.

• Protect from light, humidity, and heat.

• Maintain aseptic handling during preparation.

Safety & Handling

• For scientific research use only.

• Not for human injection or ingestion.

• Avoid inhalation or skin contact.

• Use standard PPE: gloves, lab coat, and protective eyewear.

• Dispose of materials according to institutional biosafety standards.

Why Buy from West Lab Chemicals?

🌐 High Purity Assurance: ≥99% verified by HPLC & MS.
🧪 GMP-Certified Manufacturing: Consistency and compliance guaranteed.
📄 Comprehensive Documentation: COA & MSDS included with each batch.
🚚 Global Shipping: Temperature-controlled and trackable worldwide.
💬 Expert Support: Guidance for reconstitution, solubility, and study design.
💧 Trusted by Researchers: Used in mitochondrial, metabolic, and neurodegenerative research globally.

Purity Guarantee

Each vial of Humanin 10mg from West Lab Chemicals undergoes:

• ≥99% purity testing (HPLC & MS)

• Endotoxin and sterility analysis

• Batch-specific COA and traceability certification

• GMP & ISO 9001:2015 compliant manufacturing