IGF-1 DES (1mg)

The IGF-1 DES (1mg) from West Lab Chemical is a potent truncated analog of Insulin-Like Growth Factor-1 (IGF-1), developed for cellular growth, muscle regeneration, and tissue repair research.

This high-purity peptide consists of the first 67 amino acids of native IGF-1, exhibiting 10x higher receptor affinity and faster biological activity, making it an ideal model compound for studies involving cell proliferation, tissue repair, and muscle adaptation.

For Research Use Only. Not for Human or Veterinary Consumption.

Packaging: 1mg Vial
Molecular Formula: C319H508N94O96S7
Molecular Weight: ~7,404 Da
Purity: ≥ 98% (HPLC Verified)
Grade: Analytical / Research

What is IGF-1 DES?

IGF-1 DES (1-3 IGF-1) is a shortened form of the native IGF-1 peptide, missing the first three amino acids of the N-terminus.
This modification significantly increases receptor binding potential and reduces binding affinity to IGF-binding proteins (IGFBPs), allowing for enhanced local activity in research settings.

Key Characteristics:

• Highly active IGF-1 receptor agonist

• Short biological half-life but rapid local action

• Promotes cell differentiation, proliferation, and repair

• Commonly used in muscle, tissue, and cellular growth studies

Key Features

• 🧬 Truncated IGF-1 analog (1-3 Des IGF-1)

• 💎 ≥98% purity (HPLC verified)

• ⚗️ 10x receptor affinity compared to standard IGF-1

• 🔬 Designed for cellular regeneration and metabolic studies

• 🌡️ Stable lyophilized form for reliable research performance

Mechanism of Action

IGF-1 DES binds to the IGF-1 receptor (IGF1R) and activates the PI3K-AKT-mTOR signaling pathway, a crucial cascade for cellular growth, protein synthesis, and tissue regeneration.

Unlike standard IGF-1, the DES variant shows reduced affinity for IGF-binding proteins, allowing for a greater concentration of active peptide at the receptor site.
This enhances localized anabolic and mitogenic activity, ideal for modeling cell proliferation, differentiation, and tissue recovery mechanisms.

Potential Research Applications

(For scientific research only. Not for human or animal use.)

• Cellular growth and regeneration studies

• Skeletal muscle hypertrophy modeling

• Tissue repair and healing pathways

• Protein synthesis and anabolic signaling

• Neuroprotection and metabolic function research

• IGF receptor pharmacodynamics and receptor-binding assays

Specifications

Storage & Handling

• Store at 2°C – 8°C

• Protect from light and humidity

• Reconstitute with bacteriostatic or sterile water (for laboratory use only)

• Avoid multiple freeze-thaw cycles

Why Buy from West Lab Chemical

West Lab Chemical is a leading global supplier of research-grade peptides, SARMs, and growth factors, trusted by scientific professionals and institutions worldwide.

Our Commitment to Quality:

• ≥98% peptide purity confirmed via HPLC and Mass Spectrometry

• Each vial accompanied by COA & MSDS documentation

• Manufactured in GMP-compliant laboratories

• Temperature-controlled packaging for product stability

• Reliable global shipping and dedicated support for researchers

🔬 Precision. Purity. Performance.
That’s the West Lab Chemical standard.

Purity Verification

Legal Disclaimer

This product is intended for laboratory research use only.
Not for human or veterinary consumption.
Researchers must handle in accordance with institutional safety protocols and local regulations.