IGF-1 LR3 1mg | Long R3 Insulin-Like Growth Factor Peptide

IGF-1 LR3 (Long Arg3 Insulin-Like Growth Factor-1) from West Lab Chemical is a premium receptor-grade peptide engineered for cellular growth, tissue regeneration, and longevity research.

This recombinant analog of human IGF-1 has been modified to extend half-life, enhance receptor affinity, and reduce IGF-binding protein interference — resulting in superior biological activity and extended research performance.

Each vial contains 1mg of ultra-pure IGF-1 LR3, tested and verified through HPLC and Mass Spectrometry for ≥98% purity.

For Research Use Only. Not for Human or Veterinary Use.

Packaging: 1mg Vial
Purity: ≥ 98% (HPLC Verified)
Molecular Formula: C400H625N111O115S9
Molecular Weight: ~9,115 Da
Grade: Receptor / Research

What is IGF-1 LR3?

IGF-1 LR3 (Long Arg3 Insulin-Like Growth Factor-1) is a synthetic analog of the natural Insulin-Like Growth Factor-1 protein.
It is structurally modified with:

• A 13-amino-acid extension on the N-terminus, and

• A substitution of arginine at position 3.

These modifications drastically reduce binding affinity to IGFBPs (IGF-binding proteins), increasing the amount of biologically active peptide available for receptor interaction.
As a result, IGF-1 LR3 displays 10x longer activity than native IGF-1, making it a powerful model compound for growth and repair research.

Key Features

• 💎 ≥98% Receptor Grade Purity – verified via HPLC & Mass Spectrometry

• 🧬 Extended half-life (>20 hours) vs. native IGF-1 (20 minutes)

• ⚗️ Reduced IGFBP binding = higher receptor activity

• 🌡️ Lyophilized for long-term storage stability

• 🔬 Ideal for growth, recovery, and cellular regeneration studies

Mechanism of Action

IGF-1 LR3 activates the IGF-1 receptor (IGF1R), initiating the PI3K-AKT-mTOR signaling cascade, which regulates cellular growth, repair, and protein synthesis.

Unlike native IGF-1, the LR3 variant’s structural changes make it resistant to binding proteins, allowing it to circulate longer and deliver sustained receptor stimulation.

Research models show enhanced cell differentiation, protein synthesis, and tissue regeneration, especially in skeletal muscle and connective tissues.

Research Applications

(For laboratory research use only. Not for human or animal administration.)

• Cell proliferation and growth studies

• Tissue repair and regeneration research

• Muscle hypertrophy and recovery modeling

• Protein synthesis and anabolic signaling research

• Longevity and metabolic pathway studies

Specifications

Storage & Handling

• Store at 2–8°C in a cool, dry environment.

• Protect from light and humidity.

• Reconstitute with sterile or bacteriostatic water for lab use.

• Avoid repeated freeze-thaw cycles.

Why Choose West Lab Chemical

West Lab Chemical is a trusted supplier of research-grade peptides, SARMs, and growth factors, providing exceptional purity, precision, and reliability for the scientific community.

Our Quality Assurance Includes:

• ≥98% verified peptide purity (HPLC & MS)

• GMP-compliant production standards

• COA, MSDS & analytical documentation provided

• Cold-chain shipping worldwide

• Trusted by academic and biomedical research institutions

🔬 Purity. Precision. Performance. — The West Lab Chemical commitment.

Purity Verification

Legal Disclaimer

This material is for laboratory research use only.
Not intended for human or veterinary consumption.
Handle according to institutional biosafety regulations.