IGF-1 LR3 1mg | Insulin-Like Growth Factor-1 Long R3 | Cellular Growth & Regeneration Research
IGF-1 LR3 (Long Arg3 Insulin-Like Growth Factor-1) is a synthetic analog of human IGF-1, a potent growth factor peptide that regulates cell proliferation, differentiation, and survival.
At West Lab Chemicals, we provide IGF-1 LR3 1mg (Research Grade) with ≥99% purity (HPLC & MS verified), produced in GMP-certified laboratories to ensure biological consistency, sterility, and stability.
This peptide is widely used in cell culture, muscle growth, and metabolic pathway research, where it supports cellular repair, tissue regeneration, and anabolic signaling studies.
What is IGF-1 LR3?
IGF-1 LR3 is a modified version of natural human IGF-1 (Insulin-Like Growth Factor-1) that has an extended half-life and enhanced biological potency.
The “LR3” (Long Arg3) modification replaces Arginine at position 3 and extends the amino acid chain by 13 residues, significantly reducing its binding affinity to IGF-binding proteins (IGFBPs).
As a result, IGF-1 LR3 remains active in plasma for a longer duration, allowing researchers to explore sustained IGF signaling, anabolic response, and cellular recovery with higher efficiency.
Mechanism of Action
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Binds to IGF-1 receptors (IGF-1R) on muscle, nerve, and epithelial cells.
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Activates PI3K/Akt and MAPK pathways, promoting cellular growth.
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Enhances protein synthesis and glucose utilization.
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Supports muscle hypertrophy, tissue repair, and cell survival.
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Modulates insulin sensitivity and metabolic activity in research systems.
Key Features
✅ ≥99% purity verified by HPLC & MS
✅ Extended half-life via Arg3 and N-terminal extension modifications
✅ Potent anabolic and mitogenic peptide for research applications
✅ GMP-certified production and COA documentation
✅ Stable lyophilized form with 24-month shelf life
✅ 1mg vial — perfect for growth factor and metabolic assays
Benefits (Research Context)
⚙️ Cellular Regeneration: Promotes cell division, differentiation, and growth.
⚙️ Muscle Growth Studies: Stimulates anabolic pathways and protein synthesis.
⚙️ Tissue Repair: Supports cellular recovery and regeneration post-injury.
⚙️ Anti-Aging Research: Investigates IGF pathway’s role in cellular longevity.
⚙️ Metabolic Studies: Explores insulin-like signaling and glucose uptake.
Applications / Uses (Research Only)
🔹 Cell proliferation and tissue regeneration studies
🔹 Muscle cell differentiation and hypertrophy modeling
🔹 Metabolic and insulin sensitivity research
🔹 Neuroprotective and anti-apoptotic studies
🔹 Wound healing and recovery peptide research
Composition & Technical Data
| Property | Specification |
|---|---|
| Chemical Name | Long Arg3 Insulin-Like Growth Factor-1 |
| Synonyms | IGF-1 LR3, Long R3 IGF-1, LR³IGF-1 |
| Sequence | Gly-Pro-Glu-Thr-Leu-Cys-Gly-Ala-Glu-Leu-Val-Asp-Ala-Leu-Cys-Gly-Ala-Arg-Gly-Phe-Tyr-Phe-Asn-Lys-Pro-Thr-Gly-Tyr-Gly-Ser-Ser-Ser-Arg-Leu-Tyr-Ser-Leu-Ala-Leu-Val-Asp-Thr-Leu-Gln-Phe-Val-Ser-Arg-Arg-Ala |
| CAS Number | 946870-92-4 |
| Molecular Formula | C₂₆₃H₄₀₅N₆₇O₇₈S₇ |
| Molecular Weight | ~9117 Da |
| Appearance | White to off-white lyophilized powder |
| Purity | ≥99% (HPLC verified) |
| Solubility | Soluble in sterile or bacteriostatic water |
| Form | Lyophilized peptide (Research grade) |
| Storage Conditions | –20 °C, dry and dark |
| Pack Size | 1 mg vial |
Dosage & Usage (Research Context)
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Reconstitution: Dissolve in sterile or bacteriostatic water before use.
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Concentration: Dependent on experimental assay design.
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Storage after reconstitution: Store aliquots at –20 °C.
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Handling: Avoid multiple freeze–thaw cycles.
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Note: For in vitro and laboratory research use only — not for injection or ingestion.
Storage & Stability
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Lyophilized peptide stable for 24 months at –20 °C.
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Reconstituted peptide stable for 30 days at 2–8 °C.
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Protect from direct light, moisture, and heat.
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Handle aseptically to maintain purity.
Safety & Handling
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For scientific research use only.
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Not for human or veterinary consumption.
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Avoid contact with eyes, skin, or mucous membranes.
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Use gloves, lab coat, and protective eyewear.
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Dispose of waste following institutional biosafety standards.
Why Buy from West Lab Chemicals?
🌐 Research-Grade Purity: ≥99% verified by HPLC & MS.
🧪 GMP-Compliant Manufacturing: Reliable and reproducible peptide quality.
📄 COA & MSDS Provided: Documentation with every order.
🚚 Global Shipping: Temperature-controlled and tracked delivery.
💬 Technical Assistance: Expert support for reconstitution and solubility.
💧 Trusted Worldwide: Used by universities, biotech, and pharmaceutical R&D labs globally.
Purity Guarantee
Each IGF-1 LR3 1mg vial from West Lab Chemicals undergoes:
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≥99% purity testing (HPLC & MS)
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Endotoxin and sterility screening
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Batch-specific COA and traceability
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GMP & ISO 9001:2015 certified manufacturing

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