The IGF-1 LR3 (Receptor Grade) 100mcg x 10 Vials by West Lab Chemical is a premium, long-acting analog of human Insulin-Like Growth Factor-1 (IGF-1), designed for advanced cellular growth, muscle regeneration, and longevity research.
This recombinant peptide features a 13-amino-acid N-terminal extension and a substitution of arginine at position 3, providing 10x longer half-life, enhanced receptor binding, and minimal IGF-binding protein interference.
Each vial contains 100mcg of high-purity IGF-1 LR3, supplied in a pack of 10 vials (1mg total) — ideal for controlled, repeatable laboratory applications.
For Research Use Only. Not for Human or Veterinary Use.
Packaging: 100mcg x 10 Vials (1mg Total)
Purity: ≥ 98% (HPLC Verified)
Molecular Formula: C400H625N111O115S9
Molecular Weight: ~9,115 Da
Grade: Receptor / Research
What is IGF-1 LR3?
IGF-1 LR3 (Long Arg3 Insulin-Like Growth Factor-1) is a synthetic derivative of human IGF-1, specifically engineered to extend biological activity and reduce deactivation by binding proteins.
This molecular modification allows researchers to study sustained IGF receptor activation, protein synthesis, and cellular regeneration mechanisms across multiple tissue types.
Key Functional Modifications:
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Addition of 13 amino acids at the N-terminus
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Substitution of Arginine for Glutamic Acid at position 3
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Enhanced stability in biological environments
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Extended receptor binding for long-duration activity
Key Features
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💎 Receptor Grade (≥98% Purity) – HPLC and Mass Spectrometry Verified
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🧬 10x longer half-life than native IGF-1
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⚗️ Reduced IGFBP binding = higher biological availability
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🔬 Supports advanced cell regeneration and protein synthesis research
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🌡️ Supplied as lyophilized vials for long-term stability
Mechanism of Action
IGF-1 LR3 binds directly to the IGF-1 receptor (IGF1R), stimulating the PI3K-AKT-mTOR signaling cascade, a critical pathway for cell growth, survival, and tissue regeneration.
Unlike native IGF-1, the LR3 variant resists degradation by IGF-binding proteins, resulting in sustained receptor activation and extended anabolic signaling.
In research models, IGF-1 LR3 demonstrates:
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Increased protein synthesis and cellular growth
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Enhanced muscle regeneration and recovery
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Improved tissue healing efficiency
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Activation of metabolic and longevity pathways
Research Applications
(Strictly for laboratory research use. Not for human consumption.)
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Muscle cell hypertrophy and regeneration studies
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Tissue repair and healing mechanism research
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Protein synthesis and metabolic regulation modeling
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IGF-1 receptor pharmacokinetic and pharmacodynamic studies
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Longevity, anti-aging, and performance research
Specifications
| Property | Details |
|---|---|
| Product Name | IGF-1 LR3 (Long Arg3 Insulin-Like Growth Factor-1) |
| CAS Number | 946870-92-4 |
| Form | Lyophilized Powder |
| Purity | ≥ 98% (HPLC Verified) |
| Grade | Receptor / Research |
| Total Content | 100mcg x 10 Vials (1mg Total) |
| Sequence Length | 83 Amino Acids |
| Molecular Formula | C400H625N111O115S9 |
| Molecular Weight | ~9,115 Da |
| Appearance | White to off-white crystalline powder |
| Storage Temperature | 2–8°C (Refrigerated) |
| Solubility | Water or Bacteriostatic Water |
| Shelf Life | 24 months (unreconstituted) |
Storage & Handling
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Store in 2–8°C refrigeration.
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Protect from light and humidity.
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Reconstitute only with sterile or bacteriostatic water.
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Avoid multiple freeze-thaw cycles to maintain purity and activity.
Why Choose West Lab Chemical
West Lab Chemical is a trusted manufacturer and global distributor of high-purity research peptides, SARMs, and bioactive compounds.
Each product is backed by COA, MSDS, and analytical verification, ensuring reproducibility and reliability for all research-grade use.
Our Quality Commitment:
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≥98% purity verified via HPLC & MS
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Produced in GMP-certified facilities
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Cold-chain logistics for product integrity
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Worldwide shipping with laboratory documentation
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Preferred by universities, biotech, and pharmaceutical researchers
🔬 Purity. Integrity. Innovation. — That’s the West Lab Chemical promise.
Purity Verification
| Parameter | Result |
|---|---|
| Purity (HPLC) | ≥ 98% |
| Heavy Metals | < 10 ppm |
| Endotoxin | < 0.05 EU/mg |
| Solvent Residue | < 0.1% |
| pH Range (1% Sol.) | 6.0 – 7.5 |
Legal Disclaimer
This product is intended for laboratory research use only.
It is not a drug, food additive, or cosmetic ingredient.
Not for human or veterinary use.
Researchers must follow institutional and regional biosafety regulations.

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