IGF-1 LR3 (Receptor Grade) 1mg from West Lab Chemical is a long-acting, recombinant analog of Insulin-Like Growth Factor-1 (IGF-1) designed for advanced cellular growth, muscle development, and tissue regeneration research.
With a modified amino acid sequence that extends biological activity and reduces binding to IGF-binding proteins (IGFBPs), IGF-1 LR3 exhibits enhanced stability, potency, and receptor affinity, making it a preferred peptide for growth and metabolic research applications.
For Laboratory Research Use Only. Not for Human or Veterinary Use.
Packaging: 1mg Vial
Purity: ≥ 98% (HPLC Verified)
Molecular Formula: C400H625N111O115S9
Molecular Weight: ~9,115 Da
Grade: Receptor / Research Grade
What is IGF-1 LR3?
IGF-1 LR3 (Long Arg3 IGF-1) is a synthetic derivative of human insulin-like growth factor 1 (IGF-1) that features a 13-amino-acid extension at the N-terminus and a substitution of arginine at position 3.
These modifications:
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Reduce affinity to IGFBPs (increasing free IGF-1 levels)
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Enhance biological half-life from ~20 minutes to >20 hours
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Enable sustained receptor activation for extended research modeling
Key Features
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💎 Receptor Grade Purity (≥98%) verified via HPLC & Mass Spectrometry
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🧬 Modified analog of human IGF-1 for extended activity
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⚗️ Enhanced receptor binding with reduced IGFBP interference
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🌡️ Stable lyophilized form for long-term research storage
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🔬 Ideal for cellular proliferation and muscle growth studies
Mechanism of Action
IGF-1 LR3 functions by binding to the IGF-1 receptor (IGF1R), stimulating the PI3K-AKT-mTOR signaling pathway, a critical regulator of cellular growth, survival, and protein synthesis.
Its modified structure allows it to circulate freely in the system without rapid deactivation by IGFBPs, resulting in stronger and longer-lasting receptor activation.
In research models, IGF-1 LR3 promotes:
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Enhanced protein synthesis
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Cell differentiation and regeneration
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Tissue and muscle growth simulation
Research Applications
(For laboratory use only. Not for human or animal administration.)
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Muscle cell hypertrophy and regeneration research
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Tissue healing and collagen synthesis studies
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Cell proliferation and differentiation modeling
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IGF-1 receptor pharmacodynamics
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Anti-aging and longevity pathway investigations
Specifications
| Property | Details |
|---|---|
| Product Name | IGF-1 LR3 (Long Arg3 IGF-1) |
| CAS Number | 946870-92-4 |
| Sequence Length | 83 Amino Acids |
| Purity | ≥ 98% (HPLC Verified) |
| Molecular Formula | C400H625N111O115S9 |
| Molecular Weight | ~9,115 Da |
| Form | Lyophilized Powder |
| Grade | Receptor / Research |
| Appearance | White to off-white powder |
| Storage Temperature | 2–8°C (Refrigerated) |
| Solubility | Water or Bacteriostatic Water |
Storage & Handling
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Store at 2–8°C (refrigerated).
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Protect from light and moisture.
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Reconstitute with sterile or bacteriostatic water for research solutions.
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Avoid multiple freeze-thaw cycles to maintain peptide stability.
Why Choose West Lab Chemical
At West Lab Chemical, we specialize in high-purity peptides, SARMs, and growth factors for scientific and medical research.
Every vial undergoes rigorous analytical testing to ensure consistency, stability, and potency.
Our Quality Promise:
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≥98% HPLC & MS purity
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Manufactured in GMP-compliant laboratories
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Temperature-controlled international shipping
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COA, MSDS & analytical report available for all batches
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Trusted globally by academic, pharmaceutical, and biotech researchers
🔬 Purity. Consistency. Precision. — That’s the West Lab Chemical standard.
Purity Verification
| Parameter | Result |
|---|---|
| Purity (HPLC) | ≥ 98% |
| Heavy Metals | < 10 ppm |
| Endotoxin | < 0.05 EU/mg |
| Solvent Residue | < 0.1% |
| pH Range (1% Sol.) | 6.0 – 7.5 |
Legal Disclaimer
This material is supplied for research and laboratory purposes only.
Not for human consumption or medical use.
All handling and storage must comply with institutional biosafety protocols.

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