Kisspeptin-10 10mg | Reproductive & Endocrine Research Peptide | Hypothalamic–Pituitary–Gonadal Axis Studies | West Lab Chemicals

Product Overview

Kisspeptin-10 is a synthetic decapeptide fragment derived from the endogenous peptide Kisspeptin, encoded by the KISS1 gene, known for its essential role in reproductive hormone regulation and pubertal development.

At West Lab Chemicals, we offer Kisspeptin-10 10mg (Research Grade) with ≥99% purity (HPLC & MS verified), synthesized in GMP-certified laboratories to ensure superior purity, reproducibility, and biological activity.

This peptide is extensively used in endocrine, reproductive, and neuroendocrine research to study GnRH stimulation, puberty onset, fertility signaling, and hormonal feedback loops within the HPG axis.

What is Kisspeptin-10?

Kisspeptin-10 is a bioactive fragment of the larger Kisspeptin-54 peptide, responsible for binding to and activating the GPR54 (KISS1R) receptor — a critical regulator of gonadotropin-releasing hormone (GnRH) secretion.

The discovery of Kisspeptin revolutionized reproductive biology, linking the KISS1–GPR54 signaling pathway to the control of puberty and fertility.

In research, Kisspeptin-10 is utilized to study pituitary stimulation, gonadotropin regulation, sex steroid feedback, and neuroendocrine mechanisms influencing reproductive health.

Mechanism of Action

• Binds to GPR54 (Kisspeptin receptor) expressed on GnRH neurons in the hypothalamus.

• Stimulates GnRH release, leading to secretion of LH (Luteinizing Hormone) and FSH (Follicle-Stimulating Hormone) from the anterior pituitary.

• Regulates sex steroid feedback (estrogen, progesterone, testosterone) on hypothalamic centers.

• Plays a vital role in puberty initiation, fertility, and reproductive cycle regulation.

• Exhibits potential roles in metabolic and endocrine research models.

Key Features

✅ ≥99% purity verified by HPLC & MS
✅ Synthetic decapeptide identical to natural Kisspeptin active fragment
✅ Supports research in reproductive endocrinology and puberty onset
✅ GMP-certified production with COA and MSDS documentation
✅ 10mg vial suitable for extended or multi-phase studies
✅ Stable lyophilized form with 24-month shelf life

Benefits (Research Context)

⚙️ Reproductive Regulation: Promotes LH and FSH secretion via GnRH activation.
⚙️ Fertility Studies: Enables exploration of ovulation and spermatogenesis control mechanisms.
⚙️ Puberty Research: Models hypothalamic hormone activation during sexual maturation.
⚙️ Endocrine Feedback: Allows study of estrogen/testosterone-mediated feedback loops.
⚙️ Neuroendocrine Science: Provides insight into brain–pituitary–gonadal communication.

Applications / Uses (Research Only)

🔹 Hypothalamic–pituitary–gonadal axis (HPG) research
🔹 Fertility and reproductive hormone studies
🔹 Pubertal and sexual development modeling
🔹 GnRH neuron signaling investigations
🔹 Endocrine system regulation assays

Composition & Technical Data

Dosage & Usage (Research Context)

• Reconstitution: Dissolve in sterile or bacteriostatic water prior to use.

• Concentration: Adjust according to specific research model or assay.

• Storage after reconstitution: Store aliquots at –20 °C.

• Handling: Avoid multiple freeze–thaw cycles.

• Note: For in vitro and laboratory research only — not for human or veterinary administration.

Storage & Stability

• Stable for 24 months (lyophilized) at –20 °C.

• Stable for 30 days after reconstitution at 2–8 °C.

• Protect from light, moisture, and temperature fluctuations.

• Handle aseptically during all preparation and usage phases.

Safety & Handling

• For scientific research use only.

• Not approved for human or veterinary use.

• Avoid inhalation, ingestion, or direct contact.

• Use gloves, lab coat, and eye protection.

• Dispose of materials in compliance with institutional biosafety policies.

Why Buy from West Lab Chemicals?

🌐 Research-Grade Purity: ≥99% HPLC & MS verified.
🧪 GMP Production: Guaranteed sterility and quality control.
📄 Complete Documentation: COA & MSDS with every order.
🚚 Global Shipping: Temperature-controlled and trackable.
💬 Expert Guidance: Assistance for reconstitution, solubility, and peptide storage.
💧 Trusted Worldwide: Used by reproductive and endocrine research facilities globally.

Purity Guarantee

Each Kisspeptin-10 10mg vial from West Lab Chemicals undergoes:

• ≥99% purity verification (HPLC & MS)

• Endotoxin and microbial testing

• Batch-specific COA & traceability certification

• GMP & ISO 9001:2015–certified manufacturing