Kisspeptin-10 5mg | Reproductive Hormone Peptide | Hypothalamic–Pituitary–Gonadal (HPG) Axis Research 

Kisspeptin-10 is a synthetic decapeptide fragment derived from the naturally occurring Kisspeptin (Metastin), a key signaling molecule that regulates gonadotropin-releasing hormone (GnRH) secretion.

At West Lab Chemicals, we offer Kisspeptin-10 5mg (Research Grade) with ≥99% purity (HPLC & MS verified), synthesized in GMP-certified laboratories for precision, purity, and reproducibility.

This peptide is widely used in endocrine, reproductive, and neuroendocrine studies, helping researchers explore puberty onset, fertility regulation, gonadotropin signaling, and hormonal feedback loops along the HPG axis.

What is Kisspeptin-10?

Kisspeptin-10 is the bioactive decapeptide fragment of the larger Kisspeptin-54 protein encoded by the KISS1 gene.

It binds to and activates the GPR54 (KISS1R) receptor, which in turn stimulates GnRH neurons in the hypothalamus, leading to the release of LH (Luteinizing Hormone) and FSH (Follicle-Stimulating Hormone) from the anterior pituitary.

Due to its critical role in reproductive hormone regulation, Kisspeptin-10 is a vital peptide for fertility, puberty, and neuroendocrine research.

Mechanism of Action

• Activates KISS1R (GPR54) receptors on hypothalamic GnRH neurons.

• Stimulates GnRH release, leading to LH and FSH secretion.

• Influences puberty onset, ovulation, and reproductive hormone balance.

• Modulates estrogen/testosterone feedback in the HPG axis.

• Provides a research model for reproductive and metabolic interactions.

Key Features

✅ ≥99% purity verified via HPLC & MS
✅ Bioactive decapeptide identical to endogenous Kisspeptin sequence
✅ Supports reproductive, fertility, and neuroendocrine research
✅ GMP-certified synthesis and COA documentation
✅ 5mg vial ideal for controlled and small-scale studies
✅ Excellent stability and solubility profile

Benefits (Research Context)

⚙️ Reproductive Regulation: Stimulates GnRH and gonadotropin release.
⚙️ Fertility Research: Investigates ovulation and spermatogenesis mechanisms.
⚙️ Puberty Modeling: Helps explore the onset and regulation of puberty.
⚙️ Neuroendocrine Function: Examines hypothalamic control of hormone cycles.
⚙️ Hormonal Feedback Studies: Assesses estrogen, progesterone, and testosterone regulation.

Applications / Uses (Research Only)

🔹 Reproductive endocrinology and fertility studies
🔹 Hypothalamic–pituitary–gonadal (HPG) axis research
🔹 Pubertal development and sexual maturation models
🔹 Gonadotropin and GnRH receptor signaling assays
🔹 Endocrine and hormonal feedback experiments

Composition & Technical Data

Dosage & Usage (Research Context)

• Reconstitution: Dissolve in sterile or bacteriostatic water prior to use.

• Concentration: Adjust according to experimental requirements.

• Storage after reconstitution: Store aliquots at –20 °C.

• Handling: Avoid repeated freeze–thaw cycles.

• Note: For in vitro and laboratory research only — not for human or veterinary administration.

Storage & Stability

• Stable for 24 months (lyophilized) at –20 °C.

• Stable for 30 days (reconstituted) at 2–8 °C.

• Protect from light, humidity, and heat exposure.

• Use aseptic technique during handling and reconstitution.

Safety & Handling

• Intended for scientific and laboratory research use only.

• Not for human injection, ingestion, or medical use.

• Avoid inhalation and direct contact with skin or eyes.

• Use appropriate PPE (gloves, lab coat, protective eyewear).

• Dispose of in compliance with institutional biosafety regulations.

Why Buy from West Lab Chemicals?

🌐 Exceptional Purity: ≥99% verified by HPLC & MS.
🧪 GMP Manufacturing: Guaranteed sterility and reproducibility.
📄 Complete Documentation: COA & MSDS provided with every vial.
🚚 Worldwide Shipping: Temperature-controlled, trackable delivery.
💬 Technical Expertise: Support for reconstitution and solubility guidance.
💧 Trusted Globally: Preferred supplier for reproductive and neuroendocrine research labs.

Purity Guarantee

Each Kisspeptin-10 5mg vial from West Lab Chemicals undergoes:

• ≥99% purity testing (HPLC & MS)

• Microbial and endotoxin analysis

• Batch-specific COA & traceability certification

• GMP & ISO 9001:2015–certified production