Melanostatin DM, also known as Nonapeptide-1, is a highly selective melanin synthesis inhibitor peptide used in advanced skin-brightening and hyperpigmentation-control formulations.
At West Lab Chemicals, we supply Melanostatin DM 200 mg (Topical Grade) with ≥99 % HPLC-verified purity, offering cosmetic researchers a precise and potent tool for developing safe, even-tone, and complexion-balancing skincare products.
This peptide helps reduce unwanted pigmentation, prevent new dark spots, and promote uniform skin clarity without bleaching or irritation.
What is Melanostatin DM (Nonapeptide-1)?
Melanostatin DM (INCI: Nonapeptide-1) is a bioactive synthetic peptide that works by antagonizing the α-melanocyte-stimulating hormone (α-MSH) at its receptor site, effectively down-regulating melanin production in melanocytes.
By limiting excess melanin synthesis, it contributes to brighter, clearer, and more even skin tone, making it a go-to ingredient in cosmeceutical research for pigmentation management.
Key Features
✅ ≥99 % purity verified by HPLC
✅ Suppresses overproduction of melanin
✅ Promotes balanced, luminous skin tone
✅ Reduces dark spots and uneven pigmentation
✅ Non-cytotoxic, gentle, and non-bleaching
✅ Ideal for topical research formulations
Benefits
🌟 Brightens & Evens Skin Tone: Reduces dark spots, freckles, and age-related pigmentation.
🌟 Prevents New Pigmentation: Blocks α-MSH-induced melanin overproduction.
🌟 Non-Irritating Formula: Safe for sensitive skin, no peeling or bleaching.
🌟 Enhances Radiance: Promotes a visibly healthier and luminous complexion.
🌟 Perfect for Synergistic Use: Works well with niacinamide, vitamin C derivatives, and peptides like GHK-Cu.
Applications / Uses
🔹 Brightening and skin-tone-evening creams
🔹 Anti-pigmentation serums and lotions
🔹 Post-inflammatory hyperpigmentation care
🔹 Spot-correcting topical formulations
🔹 Research on melanin-regulation peptides
Composition & Technical Data
| Property | Specification |
|---|---|
| Chemical Name | Nonapeptide-1 |
| Synonyms | Melanostatin DM |
| CAS Number | 158563-45-2 |
| Molecular Formula | C₅₁H₇₆N₁₆O₁₃ |
| Molecular Weight | 1084.25 g/mol |
| Appearance | White to off-white lyophilized powder |
| Purity | ≥ 99 % (HPLC verified) |
| Solubility | Soluble in water |
| Storage Conditions | 2 – 8 °C, dry and dark |
| Pack Size | 200 mg vial |
Dosage & Usage
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Recommended concentration: 0.1 % – 1 % in topical formulations
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Solvent: Dissolve in sterile distilled water or buffer solution
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Application: Apply formulated product to affected areas once or twice daily
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Duration: Visible results in 6–10 weeks of consistent use
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Compatibility: Stable with vitamin C derivatives, niacinamide, and hyaluronic acid
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Note: For topical and research use only; not for injection or ingestion.
Storage & Stability
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Keep sealed at 2–8 °C in a cool, dry environment.
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After reconstitution, aliquot and store frozen at –20 °C.
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Protect from light and moisture; avoid repeated freeze-thaw cycles.
Safety & Handling
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For research and cosmetic formulation purposes only.
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Not intended for medical, human, or veterinary use.
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Avoid direct eye and mucous membrane contact.
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Handle with standard lab protective equipment.
Why Buy from West Lab Chemicals?
🌐 Verified Purity: HPLC & MS tested for ≥99 % quality.
🧪 COA with Every Batch: Full analytical documentation provided.
🔒 GMP-Compliant Manufacturing: Produced under controlled conditions.
🚚 Global Shipping: Temperature-controlled packaging worldwide.
💬 Formulation Support: Technical guidance available for research projects.
💧 Cosmetic Grade Consistency: Reliable for brightening and tone-correction formulations.
Purity Guarantee
All Melanostatin DM (Nonapeptide-1) batches from West Lab Chemicals are:
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HPLC-tested for ≥99 % purity
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Verified by Mass Spectrometry
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Screened for endotoxins and microbial contamination
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Supplied with COA for traceability and transparency

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