Pentapeptide-18 (Leuphasyl) 200mg

Pricing & Availability

  • Product Code: WLC-LEU18-200

  • Pack Size: 200 mg vial

  • Purity: ≥99% (HPLC tested)

  • Form: Lyophilized powder (Topical grade)

  • Availability: In Stock

  • MOQ: 1 vial

  • Bulk Sizes: 500 mg, 1 g, 5 g available

  • Shipping: 3–5 business days worldwide

📧 For bulk orders, OEM formulation, or wholesale inquiries:
info@westlabchemicals.com

230.00 $

Pentapeptide-18, commercially known as Leuphasyl, is a biomimetic peptide designed to reduce expression wrinkles by targeting the skin’s neuromuscular activity.

At West Lab Chemicals, we supply Leuphasyl 200mg (Topical Grade) with ≥99% HPLC-tested purity, formulated specifically for cosmetic research and peptide-based skincare development.

Leuphasyl acts as a neuropeptide modulator, helping to relax facial muscle contractions and minimize dynamic wrinkles, making it a popular ingredient in anti-aging and firming formulations.


What is Pentapeptide-18 (Leuphasyl)?

Pentapeptide-18 is a synthetic peptide with the amino acid sequence Tyr-D-Ala-Gly-Phe-Leu, derived from enkephalin, a natural neurotransmitter.

It works by interfering with acetylcholine release at the neuromuscular junction, similar in concept to botulinum toxin (Botox®) but in a non-invasive, topical form.

This action helps reduce the depth of expression lines, especially around the forehead, eyes, and mouth, offering a relaxing, wrinkle-smoothing effect over time.


Key Features

✅ ≥99% purity (HPLC verified)
✅ Reduces facial muscle contractions
✅ Softens expression lines and dynamic wrinkles
✅ Improves smoothness and firmness of the skin
✅ Non-invasive, needle-free wrinkle solution
✅ Compatible with Argireline (Acetyl Hexapeptide-8) for enhanced results
✅ Ideal for cosmetic and dermatological research


Benefits

Wrinkle Reduction: Minimizes expression lines by targeting neurotransmitter activity.
Botox-Like Mechanism: Topical relaxation of facial muscles for a smoother appearance.
Non-Invasive: Safe, needle-free alternative to injectables.
Anti-Aging Synergy: Works well with Argireline and Matrixyl for comprehensive anti-wrinkle formulations.
Visible Results: Continuous use enhances firmness and elasticity within 4–8 weeks.


Applications / Uses

🔹 Anti-aging serums and creams
🔹 Expression-line and wrinkle treatment products
🔹 Eye contour and forehead wrinkle formulas
🔹 Daily peptide-based skincare
🔹 Cosmetic neuropeptide research


Composition & Technical Data

Property Specification
Chemical Name Pentapeptide-18
Commercial Name Leuphasyl
Sequence Tyr-D-Ala-Gly-Phe-Leu
CAS Number 64963-01-5
Molecular Formula C₃₀H₄₈N₆O₇
Molecular Weight 604.75 g/mol
Appearance White to off-white lyophilized powder
Purity ≥99 % (HPLC verified)
Solubility Soluble in water
Form Lyophilized powder (Topical research grade)
Storage Conditions 2 – 8 °C, dry and dark
Pack Size 200 mg vial

Dosage & Usage

  • Recommended concentration: 0.5% – 5% in topical formulations

  • Solvent: Dissolve in sterile distilled water prior to formulation blending

  • Application: Apply to expression-prone areas (forehead, eyes, mouth) once or twice daily

  • Visible Results: 4–8 weeks of consistent use

  • Compatibility: Synergistic with Argireline (Acetyl Hexapeptide-8) and Matrixyl (Palmitoyl Pentapeptide-4)

  • Note: For research and topical formulation use only; not for injection or ingestion


Storage & Stability

  • Store sealed vial at 2–8 °C in a cool, dry, dark environment.

  • After reconstitution, aliquot and freeze at –20 °C.

  • Avoid multiple freeze-thaw cycles.

  • Protect from light and moisture.


Safety & Handling

  • For cosmetic formulation and research use only.

  • Not intended for human or veterinary use.

  • Avoid direct eye and mucous membrane contact.

  • Use gloves and laboratory safety gear when handling.

  • Dispose of residual materials according to local regulations.


Why Buy from West Lab Chemicals?

🌐 High Purity: ≥99% verified by HPLC & Mass Spectrometry
🧪 COA Supplied: Every batch includes a Certificate of Analysis
🏭 GMP-Compliant Production: Manufactured under controlled laboratory conditions
🚚 Fast Global Shipping: Secure, temperature-controlled packaging
💬 Expert Support: Technical guidance for solubility and peptide formulation
💧 Trusted Worldwide: Preferred by cosmetic labs and R&D formulators


Purity Guarantee

Each batch of Leuphasyl (Pentapeptide-18) from West Lab Chemicals undergoes:

  • HPLC and MS purity verification

  • Endotoxin and microbial safety testing

  • COA batch traceability

  • Cosmetic-grade certification (≥99% purity)

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