PNC-27 10mg

PNC-27 10mg is a synthetic research peptide designed for oncological and membrane-targeting studies. It is a hybrid peptide, consisting of a p53 protein-derived sequence linked to a membrane-penetrating leader segment, enabling selective binding to cancer cell membranes that overexpress specific transport proteins.

At West Lab Chemicals, we provide PNC-27 10mg as a research-grade lyophilized peptide with ≥99% purity, verified through HPLC and LC-MS. Each vial is accompanied by a Certificate of Analysis (COA) and full batch traceability to ensure reproducibility and scientific reliability.

What is PNC-27?

PNC-27 is a synthetic peptide composed of a cell-penetrating peptide sequence (derived from Antennapedia homeodomain) fused to the MDM-2 binding domain of the human p53 tumor suppressor protein.

In laboratory studies, PNC-27 is used to explore:

• Selective cytotoxicity mechanisms against cancer cells

• Membrane pore formation and peptide–lipid interactions

• Apoptosis induction via membrane disruption models

• Cancer cell signaling and peptide targeting specificity

PNC-27’s unique structure allows it to selectively attach to and disrupt membranes of cancerous cells, while typically sparing noncancerous cells in controlled in-vitro experiments.

Key Features

✅ High Purity (≥99%) – Verified via HPLC and LC-MS testing
✅ Research Grade Only – Suitable for in-vitro and biochemical cancer research
✅ Stable Lyophilized Form – Ensures molecular stability and long shelf life
✅ Synthetic Hybrid Sequence – Combines p53 and membrane-binding domains
✅ COA Included – Analytical data provided with every order

Scientific Applications

PNC-27 10mg is widely studied across the following areas of oncology and cellular biochemistry:

• Cancer Cell Selectivity Studies: Understanding peptide–membrane binding dynamics in tumor cells.

• Membrane Biophysics: Exploring pore formation and peptide-induced cell lysis.

• Apoptosis Research: Examining programmed cell death via peptide–lipid interactions.

• Oncogenic Pathway Modeling: Investigating cancer cell-specific response mechanisms.

• Drug Design Research: Serving as a reference for anticancer peptide analog development.

Benefits for Researchers

• Provides reliable reproducibility in cell membrane and cytotoxicity assays.

• Offers unique molecular structure ideal for peptide–protein and peptide–cell interaction studies.

• Backed by HPLC/LC-MS data and COA documentation.

• Formulated for maximum peptide stability and solubility.

• Supplied in ready-to-reconstitute lyophilized form for laboratory use.

Handling & Storage

• Form: Lyophilized peptide powder

• Storage Temperature: 2–8 °C (short-term); –20 °C (long-term)

• Reconstitution: Dissolve in sterile water or PBS under aseptic conditions

• Shelf Life: 24 months under recommended storage conditions

• Safety: Laboratory use only. Use PPE. Avoid inhalation or direct contact.

Why Buy PNC-27 from West Lab Chemicals

At West Lab Chemicals, we are trusted globally for providing high-quality, laboratory-verified peptides that meet the strict standards of biochemical and cancer research.

When you purchase PNC-27 10mg from us, you receive:

• ≥99% verified purity (HPLC/LC-MS)

• Certificate of Analysis (COA) and batch traceability

• ISO 9001 and GMP-equivalent production standards

• Consistent quality and reproducibility

• Competitive pricing and bulk options

• Fast global delivery with temperature-controlled packaging

• Expert technical support for documentation and research guidance

Purity & Quality Assurance

Each batch of PNC-27 10mg is subjected to the following tests:

• HPLC purity testing (≥99%)

• LC-MS molecular verification

• Sterility and endotoxin analysis (as applicable)

• Batch traceability and COA confirmation

• Final quality review and release certification

All production is performed in ISO 9001 and GMP-equivalent facilities, ensuring compliance and precision for scientific research.

Legal & Research Disclaimer

PNC-27 10mg is sold strictly for laboratory research use only.
It is not intended for human or veterinary consumption, nor for medical, diagnostic, or therapeutic use.
All handling must be performed by qualified laboratory professionals under institutional safety protocols.

Technical Specifications