PT-141 (Bremelanotide) from West Lab Chemical is a synthetic cyclic heptapeptide analog of α-melanocyte-stimulating hormone (α-MSH).
It acts as a selective agonist of melanocortin receptors MC3R and MC4R, making it a premier model for neuroendocrine, sexual-function, and metabolic signaling research.
For Laboratory Research Use Only — Not for Human Consumption
Packaging: 10 mg Vial
Purity: ≥ 98 % (HPLC Verified)
CAS Number: 189691-06-3
Molecular Formula: C₅₀H₆₈N₁₄O₁₀
Molecular Weight: ≈ 1025.2 Da
Grade: Receptor / Research
What is PT-141 (Bremelanotide)?
PT-141 is a bioactive melanocortin analog derived from Melanotan II, engineered to focus on central melanocortin pathways rather than peripheral vasodilation.
In laboratory settings, it modulates hypothalamic neurotransmission, offering researchers a reliable tool for studying dopaminergic activity, sexual motivation, and energy regulation.
Key Features
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💎 ≥ 98 % Purity (HPLC & MS Verified)
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🧬 Selective MC3R / MC4R agonist
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⚗️ Ideal for neuroendocrine and sexual behavior research
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🔬 Cyclic peptide with enhanced receptor stability
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🧊 Lyophilized form for long shelf life and purity preservation
Mechanism of Action
PT-141 binds to melanocortin-3 and melanocortin-4 receptors in the central nervous system.
Activation of these receptors triggers cAMP signaling, influencing dopamine and hypothalamic pathways related to arousal, motivation, and energy homeostasis.
Observed Research Outcomes:
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MC3R/MC4R receptor agonism
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Enhanced sexual behavior modeling
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Dopaminergic system activation
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Central energy balance studies
Research Applications
(For scientific and laboratory research use only.)
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Melanocortin receptor signaling studies
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Neuroendocrine and CNS function modeling
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Sexual behavior and motivation research
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Dopaminergic neurotransmission pathways
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Hypothalamic energy balance investigations
Specifications
| Property | Details |
|---|---|
| Product Name | PT-141 (Bremelanotide) |
| Synonyms | Bremelanotide, PT-141 Acetate |
| CAS Number | 189691-06-3 |
| Molecular Formula | C₅₀H₆₈N₁₄O₁₀ |
| Molecular Weight | ≈ 1025.2 Da |
| Sequence | Ac-Nle-c(Asp-His-D-Phe-Arg-Trp-Lys)-OH |
| Form | Lyophilized Powder |
| Purity | ≥ 98 % (HPLC Verified) |
| Appearance | White to Off-White Powder |
| Storage Temp. | 2–8 °C (Refrigerated) |
| Solubility | Bacteriostatic Water / Sterile Water |
Storage & Handling
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Store at 2–8 °C, protected from light and moisture.
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Reconstitute with bacteriostatic or sterile water.
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Avoid multiple freeze-thaw cycles.
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For research use only.
Why Buy from West Lab Chemical
West Lab Chemical supplies receptor-grade peptides manufactured under GMP conditions, ensuring consistent purity and reliability for advanced research.
Our Quality Edge:
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≥ 98 % HPLC & MS verified purity
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Batch-specific COA & MSDS available
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GMP-certified production facilities
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Cold-chain international shipping
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Trusted by biotech and academic researchers worldwide
🧪 Precision • Purity • Performance — The West Lab Chemical Standard
Analytical Verification
| Parameter | Result |
|---|---|
| Purity (HPLC) | ≥ 98 % |
| Heavy Metals | < 10 ppm |
| Endotoxin Level | < 0.05 EU/mg |
| Solvent Residue | < 0.1 % |
Legal Disclaimer
This product is intended for laboratory research purposes only.
It is not approved for human or veterinary use.
Researchers must handle under authorized biosafety standards.

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