PT-141 (Bremelanotide) from West Lab Chemical is a synthetic peptide analog of α-melanocyte-stimulating hormone (α-MSH) that selectively activates melanocortin receptors MC3R and MC4R.
This compound is widely used in sexual function, neuroendocrine, and energy-regulation research, making it a premier model peptide for melanocortin pathway studies.
For Laboratory Research Use Only — Not for Human Consumption
Packaging: 3 mg × 10 Vials (30 mg total)
Purity: ≥ 98 % (HPLC Verified)
CAS Number: 189691-06-3
Molecular Formula: C50H68N14O10
Molecular Weight: 1025.2 Da
Grade: Receptor / Research
What is PT-141 (Bremelanotide)?
PT-141 is a cyclic heptapeptide developed from Melanotan II, but with enhanced selectivity for central melanocortin receptors.
Unlike other melanocortin analogs, PT-141 does not significantly affect skin pigmentation — instead, it acts on the hypothalamus to modulate sexual behavior, motivation, and energy balance in experimental models.
Key Features
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💎 ≥ 98 % Purity – HPLC & MS verified
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🧬 MC3R / MC4R-specific agonist for neurological studies
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⚗️ Stable cyclic structure for extended receptor activity
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🔬 Used in sexual function and neuroendocrine pathway research
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🧊 Lyophilized powder for long-term stability
Mechanism of Action
PT-141 binds with high affinity to melanocortin-3 (MC3R) and melanocortin-4 (MC4R) receptors in the brain.
Activation of these receptors influences dopaminergic and hypothalamic signaling, leading to enhanced sexual behavior, arousal, and motivation in animal studies.
In research models, this action is independent of peripheral vasodilation, differentiating PT-141 from other compounds that target vascular mechanisms.
Observed Laboratory Pathways:
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MC3R/MC4R receptor agonism
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Hypothalamic neurotransmission
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Dopaminergic modulation
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Neuroendocrine signaling
Research Applications
(For scientific and laboratory research use only.)
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Melanocortin receptor pathway studies
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Sexual motivation and arousal modeling
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Hypothalamic energy balance research
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Neuroendocrine signaling experiments
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Central nervous system pharmacology
Specifications
| Property | Details |
|---|---|
| Product Name | PT-141 (Bremelanotide) |
| Synonyms | Bremelanotide, PT-141 Acetate |
| CAS Number | 189691-06-3 |
| Molecular Formula | C50H68N14O10 |
| Molecular Weight | 1025.2 Da |
| Sequence | Ac-Nle-c[Asp-His-D-Phe-Arg-Trp-Lys]-OH |
| Form | Lyophilized Powder |
| Purity | ≥ 98 % (HPLC Verified) |
| Appearance | White to Off-White Powder |
| Storage Temp. | 2–8 °C (Refrigerated) |
| Solubility | Bacteriostatic Water / Sterile Water |
Storage & Handling
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Store at 2–8 °C, protected from light.
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Reconstitute with sterile or bacteriostatic water.
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Avoid repeated freeze-thaw cycles.
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For laboratory research only.
Why Buy from West Lab Chemical
At West Lab Chemical, we deliver receptor-grade peptides designed for advanced research in neuroendocrine and metabolic sciences.
Our Commitment:
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≥ 98 % purity (HPLC & MS verified)
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GMP-compliant manufacturing
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Batch-specific COA & MSDS
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Cold-chain worldwide shipping
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Trusted by universities and biotech labs globally
🧪 Precision • Purity • Performance — The West Lab Chemical Standard
Analytical Verification
| Parameter | Result |
|---|---|
| Purity (HPLC) | ≥ 98 % |
| Heavy Metals | < 10 ppm |
| Endotoxin Level | < 0.05 EU/mg |
| Solvent Residue | < 0.1 % |
Legal Disclaimer
This compound is intended solely for laboratory research use.
Not approved for human or veterinary use.
Handle in accordance with local biosafety regulations.

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