Syn-AKE is a breakthrough cosmetic neuropeptide developed to mimic the paralyzing effect of Waglerin-1, a compound found in the venom of the Temple Viper.
This peptide works by reducing muscle contractions that lead to expression wrinkles, providing a safe, topical alternative to Botox®.
At West Lab Chemicals, we offer Syn-AKE 200mg (Topical Grade) with ≥99% purity (HPLC verified), formulated for cosmetic peptide research, anti-aging skincare development, and advanced neuromodulation studies.
It is widely used in high-end anti-wrinkle serums, eye creams, and lifting formulations due to its fast and visible wrinkle-smoothing results.
What is Syn-AKE?
Syn-AKE (chemical name: Dipeptide Diaminobutyroyl Benzylamide Diacetate) is a synthetic tripeptide derivative designed to reproduce the activity of Waglerin-1, a natural peptide that inhibits muscle contraction signals.
By blocking the acetylcholine receptor binding at the neuromuscular junction, Syn-AKE helps reduce facial muscle tension, resulting in fewer wrinkles and smoother skin texture.
It is highly effective in targeting dynamic wrinkles — especially forehead lines, crow’s feet, and smile lines — and provides a fast, visible, and reversible muscle-relaxing effect.
Key Features
✅ ≥99% purity (HPLC & MS verified)
✅ Mimics Waglerin-1 neurotoxin mechanism
✅ Reduces expression wrinkles and dynamic lines
✅ Non-invasive, Botox-like topical effect
✅ Gentle, safe, and fast-acting formulation
✅ Ideal for anti-aging, firming, and neuromodulating skincare research
Benefits
✨ Botox-Like Effect: Reduces facial muscle movement, visibly smoothing wrinkles.
✨ Quick Results: Noticeable wrinkle reduction within weeks.
✨ Safe & Reversible: No injections, no toxicity, no downtime.
✨ Targeted Action: Ideal for forehead, crow’s feet, and smile lines.
✨ Synergy: Enhances results when combined with Argireline (Acetyl Hexapeptide-8) or Leuphasyl (Pentapeptide-18).
Applications / Uses
🔹 Anti-aging serums and creams
🔹 Eye contour and forehead wrinkle formulations
🔹 Lifting and firming skincare
🔹 Neuromodulatory cosmetic research
🔹 Anti-expression and muscle-relaxing product studies
Composition & Technical Data
| Property | Specification |
|---|---|
| Chemical Name | Dipeptide Diaminobutyroyl Benzylamide Diacetate |
| INCI Name | Syn-AKE |
| CAS Number | 794590-34-4 |
| Molecular Formula | C₃₇H₆₈N₁₀O₁₀ |
| Molecular Weight | 801.01 g/mol |
| Appearance | White to off-white lyophilized powder |
| Purity | ≥99% (HPLC verified) |
| Solubility | Soluble in water |
| Form | Lyophilized powder (Topical research grade) |
| Storage Conditions | 2–8 °C, dry and dark |
| Pack Size | 200 mg vial |
Dosage & Usage
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Recommended concentration: 1% – 4% in topical formulations
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Solvent: Dissolve in sterile distilled water before formulation blending
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Application: Apply to clean skin twice daily on wrinkle-prone areas
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Visible Results: Noticeable improvement within 4–6 weeks
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Compatibility: Excellent synergy with Argireline, SNAP-8, Matrixyl, and Leuphasyl
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Note: For topical and research use only; not for injection or ingestion
Storage & Stability
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Store sealed vial at 2–8 °C in a cool, dry, and dark place.
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After reconstitution, aliquot and store at –20 °C.
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Avoid multiple freeze-thaw cycles.
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Protect from heat, humidity, and direct sunlight.
Safety & Handling
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For cosmetic formulation and research use only.
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Not approved for human or animal consumption.
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Avoid eye and mucous membrane contact.
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Wear appropriate laboratory safety equipment when handling.
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Dispose of unused material according to local chemical regulations.
Why Buy from West Lab Chemicals?
🌐 Ultra-Pure Quality: ≥99% HPLC/MS verified
🧪 GMP Production: Manufactured under strict quality control
📄 Documentation Supplied: COA, MSDS, and batch traceability
🚚 Fast Global Shipping: Temperature-controlled packaging
💬 Technical Support: Expert help with formulation, storage, and solubility
💧 Trusted Supplier: Preferred by cosmetic researchers and peptide labs worldwide
Purity Guarantee
All Syn-AKE 200mg (Topical) from West Lab Chemicals is:
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≥99% pure (HPLC tested)
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Verified by Mass Spectrometry
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Screened for microbial and endotoxin contamination
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Supplied with batch-specific COA
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Cosmetic-grade certified

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